Male and female genital tract cancer in Singapore

Deregulated Apoptosis in Female Genital Tract Cancer

Apoptosis is initiated via the mitochondrial or the death receptor pathway. Central to the mitochondrial pathway is the release of cytochrome c from the mitochondria, leading to activation of the caspase cascade and execution of apoptosis.1 The mitochondrial pathway is regulated by the BCL-2 family of proteins, i.e. proapoptotic BAX and BAK as well as antiapoptotic BCL-2 and BCL-xL. The death r...

Cancer of the female genital tract.

• More than 71,000 women in the United States were diagnosed with a cancer affecting the reproductive organs. • More than 27,000 women in the United States died from some form of gynecologic cancer. • Uterine (endometrial) cancer is the most common gynecologic cancer. • Ovarian cancer is the most deadly gynecologic cancer. • Cervical cancer was once the leading cause of death for women in the U...

Cancer of the male genital tract.

Partial penectomy is effective in the treatment of T1 and T2 penile carcinoma with 80% fiveyear survival rates in the absence of inguinal metastases, and the residual stump is serviceable for upright micturition and sexual function. The use of micrographic surgery first introduced by Mohs in 1941 for small distally located lesions of upto one centimetre diametre achieves results comparable to p...

Female Genital Tract Tumors

Female Genital Tract Cysts

Cystic diseases in the female pelvis are common. Cysts of the female genital tract comprise a large number of physiologic and pathologic cysts. The majority of cystic pelvic masses originate in the ovary, and they can range from simple, functional cysts to malignant ovarian tumors. Non-ovarian cysts of female genital system are appeared at least as often as ovarian cysts. In this review, we aim...